MarkGLP Articles

Protocol insights
worth reading.

Research-backed guides, tool references, and protocol strategies for people running GLP-1, peptide, and performance protocols seriously.

Analytics

How to Read Your GLP-1 Adherence Data

Adherence rate, dose gaps, and weekly streaks tell different stories. Here's what each metric actually means for your protocol and how to act on low-adherence patterns before they derail a cycle.

5 min read →
Tools

Reconstitution Math for Compounded Vials

How to calculate the exact volume of bacteriostatic water needed for any vial size, and why the math changes when you switch concentration targets.

4 min read →
Tools

Half-Life Explained: When Your Dose Peaks and Troughs

Understanding the pharmacokinetic window for semaglutide, tirzepatide, and peptides so your injection timing is a deliberate choice, not a guess.

6 min read →
Research

Tirzepatide vs Semaglutide: What Matters for Tracking

Dual vs single receptor agonism shapes how each compound behaves over time. What the tracking differences look like across 12 weeks — and which metrics diverge first.

7 min read →
Protocol

Injection Site Rotation: A Protocol Primer

Rotating correctly prevents lipohypertrophy and absorption variability. A simple 7-site map and the rotation rules that keep your pharmacokinetics consistent.

3 min read →
Analytics

Body Recomp on GLP-1: Beyond the Scale

Weight on a GLP-1 protocol can mask muscle loss or significant fat change. How to track waist circumference, body fat estimates, and FFMI alongside your weight trend to see what's actually happening — and how to log it so your analytics tell the real story.

8 min read →
Protocol

Dose Escalation: When and How to Move Up

Escalation timelines differ by compound. The signals in your symptom and tolerance logs that indicate readiness — versus the signals that say stay put.

5 min read →
Protocol

BPC-157 Protocols: What to Track From Day One

BPC-157 has no clinical dosing consensus, which makes structured logging non-optional. Key metrics to establish at baseline and how to use symptom logs to assess response.

6 min read →
Research

Bloodwork on GLP-1: The Markers That Matter

A1C, fasting insulin, lipid panel, CMP — the baseline and follow-up bloodwork that gives your weight and adherence data meaningful context.

7 min read →
Research

Sleep, Mood, and GLP-1: The Signals Most Users Ignore

GLP-1 receptors are present in the brain. The sleep quality and mood data you log during early cycles often predict nausea tolerance and long-term adherence better than dose alone.

4 min read →
Tools

Inventory Forecasting: Never Run Out Mid-Cycle

A simple formula for calculating runway from current stock, your dose schedule, and typical dose waste — with a reorder buffer you can actually trust.

3 min read →
Tools

Cost-Per-Dose Math: Getting Value From Your Protocol

How to calculate true cost per dose across pen, compounded vial, and oral formats — including reconstitution waste, storage costs, and the breakeven point for annual vs monthly billing.

4 min read →
Analytics

Weight Stalls: What the Data Usually Shows

Most stalls aren't random. Adherence dips, undereating, dose timing drift, and sleep disruption each leave a different signature in the logs. How to use 4–6 weeks of data to diagnose the cause and decide whether a protocol adjustment is warranted — or whether the stall is just biological noise.

9 min read →
Protocol

TB-500 and BPC-157 Stack: A Tracking Framework

Running both simultaneously creates attribution problems. A simple symptom-tagging method that helps you separate compound effects across an 8-week stack.

5 min read →
Research

NAD+ Protocols: Dosing Schedules and What to Log

IV vs subcutaneous vs oral NAD+ have different bioavailability profiles and side-effect curves. What a baseline logging setup looks like for each format and which metrics tend to move first.

6 min read →