MarkGLP Articles

Protocol insights
worth reading.

Research-backed guides, tool references, and protocol strategies for people running GLP-1, peptide, and performance protocols seriously.

Analytics

How to Read Your GLP-1 Adherence Data

Adherence rate, dose gaps, and weekly streaks tell different stories. Here's what each metric actually means for your protocol and how to act on low-adherence patterns before they derail a cycle.

5 min read
Tools

Reconstitution Math for Compounded Vials

How to calculate the exact volume of bacteriostatic water needed for any vial size, and why the math changes when you switch concentration targets.

4 min read
Tools

Half-Life Explained: When Your Dose Peaks and Troughs

Understanding the pharmacokinetic window for semaglutide, tirzepatide, and peptides so your injection timing is a deliberate choice, not a guess.

6 min read
Research

Tirzepatide vs Semaglutide: What Matters for Tracking

Dual vs single receptor agonism shapes how each compound behaves over time. What the tracking differences look like across 12 weeks — and which metrics diverge first.

7 min read
Protocol

Injection Site Rotation: A Protocol Primer

Rotating correctly prevents lipohypertrophy and absorption variability. A simple 7-site map and the rotation rules that keep your pharmacokinetics consistent.

3 min read
Analytics

Body Recomp on GLP-1: Beyond the Scale

Weight on a GLP-1 protocol can mask muscle loss or significant fat change. How to track waist circumference, body fat estimates, and FFMI alongside your weight trend to see what's actually happening — and how to log it so your analytics tell the real story.

8 min read
Protocol

Dose Escalation: When and How to Move Up

Escalation timelines differ by compound. The signals in your symptom and tolerance logs that indicate readiness — versus the signals that say stay put.

5 min read
Protocol

BPC-157 Protocols: What to Track From Day One

BPC-157 has no clinical dosing consensus, which makes structured logging non-optional. Key metrics to establish at baseline and how to use symptom logs to assess response.

6 min read
Research

Bloodwork on GLP-1: The Markers That Matter

A1C, fasting insulin, lipid panel, CMP — the baseline and follow-up bloodwork that gives your weight and adherence data meaningful context.

7 min read
Research

Sleep, Mood, and GLP-1: The Signals Most Users Ignore

GLP-1 receptors are present in the brain. The sleep quality and mood data you log during early cycles often predict nausea tolerance and long-term adherence better than dose alone.

4 min read
Tools

Inventory Forecasting: Never Run Out Mid-Cycle

A simple formula for calculating runway from current stock, your dose schedule, and typical dose waste — with a reorder buffer you can actually trust.

3 min read
Tools

Cost-Per-Dose Math: Getting Value From Your Protocol

How to calculate true cost per dose across pen, compounded vial, and oral formats — including reconstitution waste, storage costs, and the breakeven point for annual vs monthly billing.

4 min read
Analytics

Weight Stalls: What the Data Usually Shows

Most stalls aren't random. Adherence dips, undereating, dose timing drift, and sleep disruption each leave a different signature in the logs. How to use 4–6 weeks of data to diagnose the cause and decide whether a protocol adjustment is warranted — or whether the stall is just biological noise.

9 min read
Protocol

TB-500 and BPC-157 Stack: A Tracking Framework

Running both simultaneously creates attribution problems. A simple symptom-tagging method that helps you separate compound effects across an 8-week stack.

5 min read
Research

NAD+ Protocols: Dosing Schedules and What to Log

IV vs subcutaneous vs oral NAD+ have different bioavailability profiles and side-effect curves. What a baseline logging setup looks like for each format and which metrics tend to move first.

6 min read